Structure of PDB 5c11 Chain A Binding Site BS01
Receptor Information
>5c11 Chain A (length=52) Species:
9606
(Homo sapiens) [
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SVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICIN
CA
Ligand information
>5c11 Chain B (length=7) Species:
32630
(synthetic construct) [
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ARTKQTA
Receptor-Ligand Complex Structure
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PDB
5c11
Crystal Structure of Jarid1a PHD finger bound to histone H3C4me3 peptide
Resolution
2.803 Å
Binding residue
(original residue number in PDB)
K15 V16 D17 W18 V19 Q20 D22 W28 A41 E44
Binding residue
(residue number reindexed from 1)
K15 V16 D17 W18 V19 Q20 D22 W28 A41 E44
Enzymatic activity
Enzyme Commision number
1.14.11.67
: [histone H3]-trimethyl-L-lysine(4) demethylase.
External links
PDB
RCSB:5c11
,
PDBe:5c11
,
PDBj:5c11
PDBsum
5c11
PubMed
UniProt
P29375
|KDM5A_HUMAN Lysine-specific demethylase 5A (Gene Name=KDM5A)
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