Structure of PDB 5c0j Chain A Binding Site BS01
Receptor Information
>5c0j Chain A (length=277) Species:
9606
(Homo sapiens) [
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MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMY
GCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEA
AHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEA
TLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5c0j Chain C (length=10) Species:
9606
(Homo sapiens) [
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RQFGPDWIVA
Receptor-Ligand Complex Structure
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PDB
5c0j
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution
1.64 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 R65 K66 V67 H70 T73 D77 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 M46 E64 R66 K67 V68 H71 T74 D78 Y85 R98 Y100 T144 K147 W148 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5c0j
,
PDBe:5c0j
,
PDBj:5c0j
PDBsum
5c0j
PubMed
27183389
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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