Structure of PDB 5c0g Chain A Binding Site BS01

Receptor Information
>5c0g Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5c0g Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution1.37 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 A69 H70 T73 V76 D77 Y99 T143 K146 W147 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 A69 H70 T73 V76 D77 Y99 T143 K146 W147 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5c0g, PDBe:5c0g, PDBj:5c0g
PDBsum5c0g
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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