Structure of PDB 5c0c Chain A Binding Site BS01
Receptor Information
>5c0c Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5c0c Chain C (length=10) Species:
9606
(Homo sapiens) [
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RQFGPDWIVA
Receptor-Ligand Complex Structure
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PDB
5c0c
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution
1.974 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 K66 V67 H70 D77 R97 Y99 H114 T143 K146 W147 V152 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E63 K66 V67 H70 D77 R97 Y99 H114 T143 K146 W147 V152 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5c0c
,
PDBe:5c0c
,
PDBj:5c0c
PDBsum
5c0c
PubMed
27183389
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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