Structure of PDB 5bte Chain A Binding Site BS01

Receptor Information
>5bte Chain A (length=365) Species: 284811 (Eremothecium gossypii ATCC 10895) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SELLLQRRLATTALKQPKELGYYSTNVGGELKVMDESNLSYYYLPDADIE
KHIDLSAGARKFQDEQAEAEDDTGSLHGLLQTLMEYERRKSKKVNADIIA
FRGQVKRLIHCAFGGHATDVDMYVMSFDGQLFIRAARKKLEFPTSPRESW
AYLAYYSGYKFERMALLDRPVAETPREVLESRGKQVVRNGPQYKTVVRTG
VGEHKLVLGAEVDGIFDFREPTGDNLKHYVELKVAKKVQTLKDATNFEQK
LFSVWLQCFLVGINRVIIGFRDEKFVLKSVEEFSTSEIPLLLKSTRNACV
DAIKWYGALTKWLCELPRGPEDDFKLYRLSCSRGALHLRQLHDEDLANGD
DIIPGWFREWRRSLS
Ligand information
Receptor-Ligand Complex Structure
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PDB5bte Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H114 F117 G118 G119 H120 A158 Y159 G162 Y163 D217 E235 K237 Q253 K254
Binding residue
(residue number reindexed from 1)		H110 F113 G114 G115 H116 A154 Y155 G158 Y159 D213 E231 K233 Q249 K250
Enzymatic activity
Enzyme Commision number 3.1.13.-
3.6.1.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004527 exonuclease activity
GO:0034353 mRNA 5'-diphosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006397 mRNA processing
GO:0110155 NAD-cap decapping
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5bte, PDBe:5bte, PDBj:5bte
PDBsum5bte
PubMed26101253
UniProtQ753P9|DXO_EREGS Decapping nuclease RAI1 (Gene Name=RAI1)

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