Structure of PDB 5bqz Chain A Binding Site BS01

Receptor Information
>5bqz Chain A (length=323) Species: 1454272 (Influenza A virus (A/chicken/Guangdong/S1311/2010(H6N6))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKICIGYHANNSTTKVDTILEKNVTVTHSVELLENQKEERFCKISNKAPL
DLRDCTLEGWILGNPRCGILLADQSWSYIVERPNARNGICYPGTLNEAEE
LKALIGSGERVERFEMFPKSTWTGVNTESGVSSACPLGNGPSFYRNLLWI
IKLKSSEYPVIRGTFNNTGDKSILYFWGVHHPPVTTEQNALYGSGDRYVR
MGTESMNFARSPEIAARPAVNGQRGRIDYFWSILKPGETLNVESNGNLIA
PWYAYRFVNKDSKGAIFRSNLPIENCDATCQTTEGVIRTNKTFQNVSPLW
IGECPKYVKSKSLRLATGLRNVP
Ligand information
Ligand IDSIA
InChIInChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11+/m0/s1
InChIKeySQVRNKJHWKZAKO-YRMXFSIDSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CC(=O)N[CH]1[CH](O)C[C](O)(O[CH]1[CH](O)[CH](O)CO)C(O)=O
OpenEye OEToolkits 1.5.0CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O
OpenEye OEToolkits 1.5.0CC(=O)N[C@@H]1[C@H](C[C@@](O[C@H]1[C@@H]([C@@H](CO)O)O)(C(=O)O)O)O
ACDLabs 10.04O=C(O)C1(O)OC(C(O)C(O)CO)C(NC(=O)C)C(O)C1
CACTVS 3.341CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
FormulaC11 H19 N O9
NameN-acetyl-alpha-neuraminic acid;
N-acetylneuraminic acid;
sialic acid;
alpha-sialic acid;
O-SIALIC ACID
ChEMBLCHEMBL1234621
DrugBankDB03721
ZINCZINC000004081651
PDB chain5bqz Chain G Residue 4 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5bqz Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		Y91 V131 S132 S133 W149 H180 E187 Q223
Binding residue
(residue number reindexed from 1)		Y91 V131 S132 S133 W149 H180 E187 Q223
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5bqz, PDBe:5bqz, PDBj:5bqz
PDBsum5bqz
PubMed26226046
UniProtA0A067YZV9

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