Structure of PDB 5b5u Chain A Binding Site BS01

Receptor Information
>5b5u Chain A (length=175) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKILLIGMGGTIASVKGENGYEASLSVKEVLDIAGIKDCEDCDFLDLKNV
DSTLIQPEDWVDLAETLYKNVKKYDGIIVTHGTDTLAYTSSMISFMLRNP
PIPIVFTGSMIPATEENSDAPLNLQTAIKFATSGIRGVYVAFNGKVMLGV
RTSKVRTMSRDAFESINYPIIAELR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5b5u Heat induces end to end repetitive association in P. furiosus L-asparaginase which enables its thermophilic property.
Resolution2.61 Å
Binding residue
(original residue number in PDB)
I171 A172 E173 L174 R175
Binding residue
(residue number reindexed from 1)
I171 A172 E173 L174 R175
Enzymatic activity
Catalytic site (original residue number in PDB) T11 Y21 T83 D84 K154
Catalytic site (residue number reindexed from 1) T11 Y21 T83 D84 K154
Enzyme Commision number 3.5.1.1: asparaginase.
External links
PDB RCSB:5b5u, PDBe:5b5u, PDBj:5b5u
PDBsum5b5u
PubMed33303914
UniProtQ8TZE8|ASPG_PYRFU L-asparaginase (Gene Name=PF2047)

[Back to BioLiP]