Structure of PDB 5b5b Chain A Binding Site BS01

Receptor Information
>5b5b Chain A (length=249) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPLKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLS
MLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRS
NQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNL
HEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPG
SHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
Ligand information
Receptor-Ligand Complex Structure
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PDB5b5b Helix12-Stabilization Antagonist of Vitamin D Receptor
Resolution2.0 Å
Binding residue
(original residue number in PDB)
I238 K242 D253 K260 P412 E416
Binding residue
(residue number reindexed from 1)
I67 K71 D82 K89 P241 E245
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5b5b, PDBe:5b5b, PDBj:5b5b
PDBsum5b5b
PubMed27294600
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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