Structure of PDB 5b2p Chain A Binding Site BS01 |
| >5b2p Chain A (length=1455) Species: 401614 (Francisella tularensis subsp. novicida U112)
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MNFKILPIAIDLGVKNTGVFSAFYQKGTSLERLDNKNGKVYELSKDSYTL
LMNNRTARRHQRRGIDRKQLVKRLFKLIWTEQLNLEWDKDTQQAISFLFN
RRGFSFITDGYSVKAILMDIFDDYNGEDDSYLKLATEQESKISEIYNKLM
QKILEFKLMKLCTDIKDDTLKEITSYEFELLADYLANYSESLKTQKFYNI
QEFLKRHATINDRILDTLLTDDLDIWNFNFELHHFVFAVNKIKSEMASGG
RHRSQYFQEITNVLDENNHQEGYLKNFCENLHNKKYSNLSVKNLVNLIGN
LSNLELKPLRKYFNDKIHAKADHWDEQKFTETYCHWILGEWRVGVKDQDK
KDGAKYSYKDLCNELKQKVTKAGLVDFLLELDPCRTIPPYLDNNNRKPPK
CQSLILNPKFLDNQYPNWQQYLQELKKLQSIQNYLDSFETDLKVLKSSKD
QPYFVEYKSSNQQIASGQRDYKDLDARILQFIFDRVKASDELLLNEIYFQ
AKKLKQESSKKLDEVIANSQLSQILKSQHTNGIFEQGTFLHLVCKYYKQR
QRARDSRLYIMPEYRYDKKLHKYNNTGRFDDDNQLLTYCNHKPRQKRYQL
LNDLAGVLQVSPNFLKDKIGSDDDLFISKWLVEHIRGFKKACEDSLKIQK
DNRGLLNHKINIARNTKGKCEKEIFNLICKIEGYKHGLAYELGVLLFGEP
NEASKPEFDRKIKKFNSIYSFAQIQQIAFAERKGNANTCAVCSADNAHRM
QQIKIILSAKAQRLPAIPTRIVDGAVKKMATILAKNIVDDNWQNIKQVLS
AKHQLHIPIITESNAFEFEPALADVKGKSLKDRRKKALERISPENIFKDK
NNRIKEFAEELDHIIPRTLNDEANLICVTGNRIFCLRDNYRSFINLTPQE
QKAFRHALFLADENPIKQAVIRAINNRNRTFVNGTQRYFAEVLANNIYLR
AKKENLNTDKISFDYFGIPTIGNGRGIAEIRQLYEKVDSDIQAYAKGDKP
QASYSHLIDAMLAFCIAADEHRNDGSIGLEIDKNYSLYPDIFSQIKITDN
EFSDKKLVRKKAIEGFNTHRQMTRDGIYAENYLPILIHKELNEVRKGYTW
KNSEEIKIFKGKKYDIQQLNNLVYCLKFVDKPISIDIQISTLEELRNILT
TNNIAATAEYYYINLKTQKLHEYYIENYNTALGYKKYSKEMEFLRSLAYR
SERVKIKSIDDVKQVLDKDSNFIIGKITLPFKKEWQRLYREWQNTTIKDD
YEFLKSFFNVKSITKLHKKVRKDFSLPISTNEGKFLVKRKTWDNNFIYQI
LNDSDSRADGTKPFIPAFDISKNEIVEAIIDSFTSKNIFWLPKNIELQKV
DNKNIFAIDTSKWFEVETPSDLRDIGIATIQYKIDNNSRPKVRVKLDYVI
DDDSKINYFMNHSLLKSRYPDKVLEILKQSTIIEFESSGFNKTIKEMLGM
KLAGI |
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| PDB | 5b2p Structure and Engineering of Francisella novicida Cas9 |
| Resolution | 1.7 Å |
Binding residue
(original residue number in PDB) | Y48 T49 L51 M52 R55 T56 R58 R59 H60 R62 R63 I65 Q69 K72 R73 Q92 Q93 S96 F97 N100 R101 R102 G103 F104 G308 R310 Q329 E330 G331 Y332 L365 R369 F372 N373 D374 K375 H377 A378 H394 E399 R401 L450 D451 N452 N453 N454 R455 K456 P457 K459 S506 S507 K508 Y512 Q522 I523 S525 G526 Q527 R622 K640 Y641 N642 N643 R646 K660 R662 Q663 K664 R665 Y666 D671 Q717 K718 Q798 Q801 R807 N812 T813 R849 P854 D859 G860 K871 K912 K914 R1047 S1048 N1051 N1084 T1086 K1109 R1226 K1227 F1233 T1235 H1236 R1237 Q1238 M1239 T1240 I1244 Y1245 A1246 Y1329 N1331 Q1335 E1369 R1370 K1372 P1397 E1401 F1425 V1427 K1435 K1436 V1437 R1438 K1439 D1440 S1442 L1443 P1444 R1456 T1458 W1459 I1464 Q1466 S1499 S1502 I1505 |
Binding residue
(residue number reindexed from 1) | Y48 T49 L51 M52 R55 T56 R58 R59 H60 R62 R63 I65 Q69 K72 R73 Q92 Q93 S96 F97 N100 R101 R102 G103 F104 G249 R251 Q270 E271 G272 Y273 L306 R310 F313 N314 D315 K316 H318 A319 H335 E340 R342 L391 D392 N393 N394 N395 R396 K397 P398 K400 S447 S448 K449 Y453 Q463 I464 S466 G467 Q468 R554 K572 Y573 N574 N575 R578 K592 R594 Q595 K596 R597 Y598 D603 Q649 K650 Q723 Q726 R732 N737 T738 R763 P768 D773 G774 K785 K826 K828 R891 S892 N895 N928 T930 K953 R1059 K1060 F1066 T1068 H1069 R1070 Q1071 M1072 T1073 I1077 Y1078 A1079 Y1162 N1164 Q1168 E1202 R1203 K1205 P1230 E1234 F1258 V1260 K1268 K1269 V1270 R1271 K1272 D1273 S1275 L1276 P1277 R1289 T1291 W1292 I1297 Q1299 S1332 S1335 I1338 |
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