Structure of PDB 5azb Chain A Binding Site BS01

Receptor Information
>5azb Chain A (length=284) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGW
TKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGEL
WGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYE
LLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQF
TGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSP
Ligand information
Ligand IDPLM
InChIInChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)
InChIKeyIPCSVZSSVZVIGE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)O
ACDLabs 10.04O=C(O)CCCCCCCCCCCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(O)=O
FormulaC16 H32 O2
NamePALMITIC ACID
ChEMBLCHEMBL82293
DrugBankDB03796
ZINCZINC000006072466
PDB chain5azb Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5azb Crystal structure of E. coli lipoprotein diacylglyceryl transferase
Resolution1.6 Å
Binding residue
(original residue number in PDB)		F102 L139 Y259 M262
Binding residue
(residue number reindexed from 1)		F100 L137 Y257 M260
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.145: phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
Gene Ontology
Molecular Function
GO:0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
GO:0016740 transferase activity
Biological Process
GO:0042158 lipoprotein biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0009898 cytoplasmic side of plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5azb, PDBe:5azb, PDBj:5azb
PDBsum5azb
PubMed26729647
UniProtP60955|LGT_ECOLI Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase (Gene Name=lgt)

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