Structure of PDB 5axw Chain A Binding Site BS01 |
| >5axw Chain A (length=1043)
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RNYILGLDIGITSVGYGIIDYETRDVIDAGVRLFKEANVENNEGRRSKRG
ARRLKRRRRHRIQRVKKLLFDYNLLTDHSELSGINPYEARVKGLSQKLSE
EEFSAALLHLAKRRGVHNVNEVEEDTGNELSTKEQISRNSKALEEKYVAE
LQLERLKKDGEVRGSINRFKTSDYVKEAKQLLKVQKAYHQLDQSFIDTYI
DLLETRRTYYEGPGEGSPFGWKDIKEWYEMLMGHCTYFPEELRSVKYAYN
ADLYNALNDLNNLVITRDENEKLEYYEKFQIIENVFKQKKKPTLKQIAKE
ILVNEEDIKGYRVTSTGKPEFTNLKVYHDIKDITARKEIIENAELLDQIA
KILTIYQSSEDIQEELTNLNSELTQEEIEQISNLKGYTGTHNLSLKAINL
ILDELWHTNDNQIAIFNRLKLVPKKVDLSQQKEIPTTLVDDFILSPVVKR
SFIQSIKVINAIIKKYGLPNDIIIELAREKNSKDAQKMINEMQKRNRQTN
ERIEEIIRTTGKENAKYLIEKIKLHDMQEGKCLYSLEAIPLEDLLNNPFN
YEVDHIIPRSVSFDNSFNNKVLVKQEEASKKGNRTPFQYLSSSDSKISYE
TFKKHILNLAKGKGRISKTKKEYLLEERDINRFSVQKDFINRNLVDTRYA
TRGLMNLLRSYFRVNNLDVKVKSINGGFTSFLRRKWKFKKERNKGYKHHA
EDALIIANADFIFKEWKKLDKAKKVMENQMFMPEIETEQEYKEIFITPHQ
IKHIKDFKDYKYSHRVDKKPNRELINDTLYSTRKDDKGNTLIVNNLNGLY
DKDNDKLKKLINKSPEKLLMYHHDPQTYQKLKLIMEQYGDEKNPLYKYYE
ETGNYLTKYSKKDNGPVIKKIKYYGNKLNAHLDITDDYPNSRNKVVKLSL
KPYRFDVYLDNGVYKFVTVKNLDVIKKENYYEVNSKAYEEAKKLKKISNQ
AEFIASFYNNDLIKINGELYRVIGVNNDLLNRIEVNMIDITYREYLENMN
DKRPPRIIKTIASKTQSIKKYSTDILGNLYEVKSKKHPQIIKK |
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| PDB | 5axw Crystal Structure of Staphylococcus aureus Cas9. |
| Resolution | 2.7 Å |
Binding residue
(original residue number in PDB) | V41 N43 N44 R47 R48 K50 R51 R54 R55 L56 K57 R58 R59 R61 H62 R66 P88 Y89 H111 K114 R115 R116 G117 G162 E163 V164 R165 G166 N169 R170 R208 R209 T210 Y211 E213 G214 P215 G216 S219 F221 T238 Y239 K248 Y256 N257 R314 H393 N394 Q414 R452 K459 R774 K778 N780 R781 E782 L783 L788 S790 R792 N804 L828 H832 D833 K867 Y868 S869 K870 V876 I877 K878 K879 I880 K881 D896 Y897 S900 R901 V904 K906 K935 |
Binding residue
(residue number reindexed from 1) | V39 N41 N42 R45 R46 K48 R49 R52 R53 L54 K55 R56 R57 R59 H60 R64 P86 Y87 H109 K112 R113 R114 G115 G160 E161 V162 R163 G164 N167 R168 R206 R207 T208 Y209 E211 G212 P213 G214 S217 F219 T236 Y237 K246 Y254 N255 R312 H391 N392 Q412 R450 K457 R765 K769 N771 R772 E773 L774 L779 S781 R783 N795 L819 H823 D824 K858 Y859 S860 K861 V867 I868 K869 K870 I871 K872 D887 Y888 S891 R892 V895 K897 K926 |
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