Structure of PDB 5awu Chain A Binding Site BS01

Receptor Information
>5awu Chain A (length=265) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITRHFANNPSP
AALTFRVINFSRLEHVLPNPQLLCCDANTKEFWVNMPNLMTHLKKVSEQK
PQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDA
MTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKS
ENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFS
LIKKRFAAGKYLADN
Ligand information
Receptor-Ligand Complex Structure
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PDB5awu Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
P561 V562 A564 A565 S593 P595 Y668 N670 S813 R818
Binding residue
(residue number reindexed from 1)
P3 V4 A6 A7 S35 P37 Y105 N107 S250 R255
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0072583 clathrin-dependent endocytosis

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Biological Process
External links
PDB RCSB:5awu, PDBe:5awu, PDBj:5awu
PDBsum5awu
PubMed26822536
UniProtQ9BQI5|SGIP1_HUMAN SH3-containing GRB2-like protein 3-interacting protein 1 (Gene Name=SGIP1)

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