Structure of PDB 5awh Chain A Binding Site BS01 |
| >5awh Chain A (length=759) Species: 349102 (Cereibacter sphaeroides ATCC 17025)
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HMQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKL
FHLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRP
FTFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRV
GVFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQPGERGLLGRVRAI
SDDMVQLFEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALD
DQEAGYRTGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQA
RNVRLAPKVEYVFDRTGAKSAEYAWRGLSQFGPFDRPSFANRSPRILVVY
PSSTQGKVENFLSAFRDGMGSNYSGFSKGFVDLMGLTKVEFVMCPVEVSS
ADRNGAHTKYNSAIEDKLAGAGEVHAGIVVLFEDHARLPDDRNPYIHTKS
LLLTLGVPTQQVRMPTVLLEPKSLQYTLQNFSIATYAKLNGTPWTVNHDK
AINDELVVGMGLAELSGSRTEKRQRFVGITTVFAGDGSYLLGNVSKECEY
EGYSDAIRESMTGILRELKKRNNWRPGDTVRVVFHAHRPLKRVDVASIVF
ECTREIGSDQNIQMAFVTVSHDHPFVLIDRSERGLEAYKGSTARKGVFAP
PRGAISRVGRLTRLLAVNSPQLIKRANTPLPTPLLVSLHPDSTFKDVDYL
AEQALKFTSLSWRSTLPAATPVTIFYSERIAELLGRLKSIPNWSSANLNI
KLKWSRWFL |
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| PDB | 5awh Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute. |
| Resolution | 2.0 Å |
Binding residue
(original residue number in PDB) | P43 R151 G175 M176 R177 Y178 R209 G210 L211 E242 G243 K245 R275 A454 Y463 K467 Q478 Q479 V480 R481 T484 T495 N498 F499 K506 R537 R541 R543 R606 K609 R610 K692 R731 S732 P735 A737 F743 R754 L777 |
Binding residue
(residue number reindexed from 1) | P25 R133 G157 M158 R159 Y160 R191 G192 L193 E224 G225 K227 R257 A436 Y445 K449 Q460 Q461 V462 R463 T466 T477 N480 F481 K488 R519 R523 R525 R588 K591 R592 K674 R713 S714 P717 A719 F725 R736 L759 |
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| Enzyme Commision number |
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