Structure of PDB 5ao0 Chain A Binding Site BS01

Receptor Information

>5ao0 Chain A (length=439) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IHVDTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPG
ASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLG
HGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGL
IPEEDICFIKEQIVGPLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFA
RDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRN
SLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDME
AYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIK
IKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMHVSFYCKTAPNR
AIREQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQ

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

5ao0 Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5ao0 Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Resolution	3.731 Å
Binding residue (original residue number in PDB)	H167 H206 D207 D311
Binding residue (residue number reindexed from 1)	H58 H97 D98 D194
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.5.-

External links

PDB	RCSB:5ao0, PDBe:5ao0, PDBj:5ao0
PDBsum	5ao0
PubMed	26431200
UniProt	Q9Y3Z3\|SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Gene Name=SAMHD1)

[Back to BioLiP]