Structure of PDB 5akn Chain A Binding Site BS01

Receptor Information
>5akn Chain A (length=178) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITAKSENLIKQHIAPL
MQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMRE
QIAFIKGLYVAEGDMTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDD
HRHGVYVLNISLRDRIKFVHTILSSHLN
Ligand information
Receptor-Ligand Complex Structure
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PDB5akn Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
D21 T41 A42 K43 T76 R124 T150 H152 D154 R157 S166 L167
Binding residue
(residue number reindexed from 1)
D16 T36 A37 K38 T71 R119 T145 H147 D149 R152 S161 L162
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function

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Biological Process
External links
PDB RCSB:5akn, PDBe:5akn, PDBj:5akn
PDBsum5akn
PubMed26045557
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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