Structure of PDB 5akm Chain A Binding Site BS01

Receptor Information

>5akm Chain A (length=183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ENVSGISAYLLGLIISDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSHLNPLPP

Ligand information

>5akm Chain B (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gccttgccgggtaa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5akm Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	D21 T41 K43 T76 R77 R124 T150 H152 D154 R157 S166 L167
Binding residue (residue number reindexed from 1)	D17 T37 K39 T72 R73 R120 T146 H148 D150 R153 S162 L163

Enzymatic activity

Enzyme Commision number

3.1.-.-

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

	Biological Process
GO:0006314	intron homing
GO:0016539	intein-mediated protein splicing

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Molecular Function

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Biological Process

External links

PDB	RCSB:5akm, PDBe:5akm, PDBj:5akm
PDBsum	5akm
PubMed	26045557
UniProt	P21505\|DMO1_DESMO Homing endonuclease I-DmoI

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