Structure of PDB 5aho Chain A Binding Site BS01

Receptor Information

>5aho Chain A (length=314) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SMNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLY
CSPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANH
CPGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNC
NPALVLPSRQEAAHQIVQLIRKHPQHNIKIGLYSLGKESLLEQLALEFQT
WVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTH
PTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVS
RRPCGGFQDSLSPR

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

5aho Chain A Residue 1320 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5aho The Structures of the Snm1A and Snm1B/Apollo Nuclease Domains Reveal a Potential Basis for Their Distinct DNA Processing Activities.
Resolution	2.16 Å
Binding residue (original residue number in PDB)	H36 D120
Binding residue (residue number reindexed from 1)	H37 D121
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.-.-
3.5.2.6: beta-lactamase.

External links

PDB	RCSB:5aho, PDBe:5aho, PDBj:5aho
PDBsum	5aho
PubMed	26582912
UniProt	Q9H816\|DCR1B_HUMAN 5' exonuclease Apollo (Gene Name=DCLRE1B)

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