Structure of PDB 5afw Chain A Binding Site BS01
Receptor Information
>5afw Chain A (length=163) Species:
9606
(Homo sapiens) [
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EFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYL
IKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWYNCQQEL
TDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIS
KKFQACIDEYFSR
Ligand information
>5afw Chain B (length=7) Species:
9606
(Homo sapiens) [
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TSRRKRA
Receptor-Ligand Complex Structure
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PDB
5afw
Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
A290 T293 Y295 W322 W325 D408 W423 E424 D425 L428
Binding residue
(residue number reindexed from 1)
A21 T24 Y26 W53 W56 D128 W143 E144 D145 L148
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
External links
PDB
RCSB:5afw
,
PDBe:5afw
,
PDBj:5afw
PDBsum
5afw
PubMed
26751641
UniProt
O14646
|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)
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