Structure of PDB 5a2o Chain A Binding Site BS01

Receptor Information
>5a2o Chain A (length=470) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATA
ANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLST
IIPSGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTY
FFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAG
TNRYRFKKLIGSPMTQVAAVIVAAWRNRKLETLSTLTDVEEVKQIVRMLP
IWATCILFWTVHAQLTTLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLL
TTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAALVELKR
LRTAHAHGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKGMKGMSTGLL
LSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGRLYNFYWLVAVLVA
LNFLIFLVFSKWYVYKEKRL
Ligand information
Ligand IDNO3
InChIInChI=1S/NO3/c2-1(3)4/q-1
InChIKeyNHNBFGGVMKEFGY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-][N+]([O-])=O
OpenEye OEToolkits 1.5.0[N+](=O)([O-])[O-]
FormulaN O3
NameNITRATE ION
ChEMBLCHEMBL186200
DrugBankDB14049
ZINC
PDB chain5a2o Chain A Residue 1574 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5a2o Molecular Basis of Nitrate Uptake by the Plant Nitrate Transporter Nrt1.1.
Resolution3.71 Å
Binding residue
(original residue number in PDB)		H356 T360
Binding residue
(residue number reindexed from 1)		H262 T266
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015112 nitrate transmembrane transporter activity
GO:0015293 symporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0009414 response to water deprivation
GO:0009635 response to herbicide
GO:0009734 auxin-activated signaling pathway
GO:0010167 response to nitrate
GO:0010540 basipetal auxin transport
GO:0015706 nitrate transmembrane transport
GO:0042128 nitrate assimilation
GO:0048527 lateral root development
GO:0048573 photoperiodism, flowering
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5a2o, PDBe:5a2o, PDBj:5a2o
PDBsum5a2o
PubMed24572366
UniProtQ05085|PTR7_ARATH Protein NRT1/ PTR FAMILY 6.3 (Gene Name=NPF6.3)

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