Structure of PDB 4zxl Chain A Binding Site BS01

Receptor Information

>4zxl Chain A (length=579) Species: 195103 (Clostridium perfringens ATCC 13124) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTA
NNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSN
DGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGF
YGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQR
MQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMG
VRSFAIYWDNIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTG
AMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYD
RNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSK
ISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNK
TWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNN
LKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKE
IAQNKLNTALSSFAVISEKVAQSFIQEAL

Ligand information

>4zxl Chain H (length=4) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PSTA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4zxl A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development.
Resolution	2.6 Å
Binding residue (original residue number in PDB)	Y189 N298 D401 Y402 W490
Binding residue (residue number reindexed from 1)	Y151 N260 D363 Y364 W452

Enzymatic activity

Enzyme Commision number

3.2.1.169: protein O-GlcNAcase.

External links

PDB	RCSB:4zxl, PDBe:4zxl, PDBj:4zxl
PDBsum	4zxl
PubMed	26348912
UniProt	Q0TR53\|OGA_CLOP1 O-GlcNAcase NagJ (Gene Name=nagJ)

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