Structure of PDB 4zw2 Chain A Binding Site BS01

Receptor Information
>4zw2 Chain A (length=319) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
REALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAIT
FEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLR
QNRLSSSKHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMM
QKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS
LAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITS
PKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDAC
EHLAEYLEAYWKATHPPSS
Ligand information
Receptor-Ligand Complex Structure
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PDB4zw2 Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta 1a reveal critical roles of domain interactions for stability.
Resolution1.86 Å
Binding residue
(original residue number in PDB)		M163 M164 K166 A167 V267 L271 S274 E307 N308 L310 A313
Binding residue
(residue number reindexed from 1)		M149 M150 K152 A153 V253 L257 S260 E293 N294 L296 A299
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005245 voltage-gated calcium channel activity
Biological Process
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005891 voltage-gated calcium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zw2, PDBe:4zw2, PDBj:4zw2
PDBsum4zw2
PubMed28351836
UniProtQ8R3Z5|CACB1_MOUSE Voltage-dependent L-type calcium channel subunit beta-1 (Gene Name=Cacnb1)

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