Structure of PDB 4ztt Chain A Binding Site BS01

Receptor Information
>4ztt Chain A (length=162) Species: 536056 (Escherichia coli DH1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKPEMIEKLNEQMNLELYASLLYQQMSAWCSYHTFEGAAAFLRRHAQEEM
THMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKI
NELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGL
YFIDKELSTLDT
Ligand information
Ligand IDFEO
InChIInChI=1S/2Fe.O
InChIKeyNPMYUMBHPJGBFA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Fe]O[Fe]
OpenEye OEToolkits 1.5.0O([Fe])[Fe]
FormulaFe2 O
NameMU-OXO-DIIRON
ChEMBL
DrugBank
ZINC
PDB chain4ztt Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ztt Structural Basis of Novel Iron-Uptake Route and Reaction Intermediates in Ferritins from Gram-Negative Bacteria.
Resolution1.83 Å
Binding residue
(original residue number in PDB)		E17 E50 H53 E94 Q127 E130
Binding residue
(residue number reindexed from 1)		E16 E49 H52 E93 Q126 E129
Annotation score3
Enzymatic activity
Enzyme Commision number 1.16.3.2: bacterial non-heme ferritin.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0140315 iron ion sequestering activity
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0006974 DNA damage response
GO:0006979 response to oxidative stress
GO:0071281 cellular response to iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ztt, PDBe:4ztt, PDBj:4ztt
PDBsum4ztt
PubMed27777002
UniProtP0A998|FTNA_ECOLI Bacterial non-heme ferritin (Gene Name=ftnA)

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