Structure of PDB 4zq0 Chain A Binding Site BS01
Receptor Information
>4zq0 Chain A (length=234) Species:
658858
(Giardia lamblia P15) [
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FTREDYVFMAQLNENAERYDEMVETMRKISGMEGELSDKERNLLSVAYKN
VIGPRRAAWRIVSSIEAKEKGRQKPNAKRIEQIRVYRQKIEKELSDICND
ILKLLQEQFVPRSTNADAKVFYYKMQGDYYRYLAEYSSGEDKEKIAGSAL
NAYNSAFEISQQLPPTHPIRLGLALNFSVFYYEILASPDRACELARKAFD
AAITDLDKLTEESYKDSTLIMQLLRDNLNLWVTD
Ligand information
>4zq0 Chain E (length=4) Species:
32630
(synthetic construct) [
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ASAP
Receptor-Ligand Complex Structure
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PDB
4zq0
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
K53 R60 R135 Y136 L179 N180 N231
Binding residue
(residue number reindexed from 1)
K49 R56 R131 Y132 L175 N176 N227
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003779
actin binding
GO:0005515
protein binding
GO:0019900
kinase binding
GO:0042802
identical protein binding
GO:0042803
protein homodimerization activity
GO:0050815
phosphoserine residue binding
GO:0051219
phosphoprotein binding
Biological Process
GO:0000165
MAPK cascade
GO:0007165
signal transduction
GO:0008104
protein localization
GO:0030010
establishment of cell polarity
GO:0030036
actin cytoskeleton organization
GO:0051289
protein homotetramerization
GO:0051495
positive regulation of cytoskeleton organization
GO:0070207
protein homotrimerization
GO:0097298
regulation of nucleus size
Cellular Component
GO:0005634
nucleus
GO:0005635
nuclear envelope
GO:0005737
cytoplasm
GO:0005783
endoplasmic reticulum
GO:0005819
spindle
GO:0005856
cytoskeleton
GO:0005930
axoneme
GO:0031514
motile cilium
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4zq0
,
PDBe:4zq0
,
PDBj:4zq0
PDBsum
4zq0
PubMed
26551337
UniProt
E2RU97
|1433_GIAIC 14-3-3 protein (Gene Name=GL50803_006430)
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