Structure of PDB 4zns Chain A Binding Site BS01

Receptor Information
>4zns Chain A (length=231) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFLKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKNVVPLSDLLLEMLDAHRLHA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zns Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution1.86 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 D538 E542
Binding residue
(residue number reindexed from 1)
I49 K53 V67 D218 E222
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4zns, PDBe:4zns, PDBj:4zns
PDBsum4zns
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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