Structure of PDB 4zih Chain A Binding Site BS01

Receptor Information
>4zih Chain A (length=145) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGGPTSSEQIMKTGALLLQGFIQDRAGRDPVPQDASTKKLSESLKRIGDE
LDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASK
LVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zih Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
L70 N73 L76 M79 I80 D98 M99 N106 G108 R109 F116
Binding residue
(residue number reindexed from 1)
L51 N54 L57 M60 I61 D79 M80 N87 G89 R90 F97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:4zih, PDBe:4zih, PDBj:4zih
PDBsum4zih
PubMed26158515
UniProtQ07812|BAX_HUMAN Apoptosis regulator BAX (Gene Name=BAX)

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