Structure of PDB 4zdu Chain A Binding Site BS01

Receptor Information
>4zdu Chain A (length=416) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WSVEDIVKGINSNNLESQLQATQAARKLLSPIDNIIRAGLIPKFVSFLGK
TDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISE
QAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLT
WTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTD
GPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQK
VIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVP
FLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLS
AKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE
NESVYKASLNLIEKYF
Ligand information
>4zdu Chain B (length=12) Species: 211044 (Influenza A virus (A/Puerto Rico/8/1934(H1N1))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SQGTKRSYEQME
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zdu Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Resolution2.3 Å
Binding residue
(original residue number in PDB)		K240 R315 V321 T322 D325 K353 W357 S360 N361 A364 G365 E396 W399 N403
Binding residue
(residue number reindexed from 1)		K160 R235 V241 T242 D245 K273 W277 S280 N281 A284 G285 E316 W319 N323
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4zdu, PDBe:4zdu, PDBj:4zdu
PDBsum4zdu
PubMed26456934
UniProtP52293|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)

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