Structure of PDB 4zdm Chain A Binding Site BS01

Receptor Information
>4zdm Chain A (length=249) Species: 34499 (Pleurobrachia bachei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNNLNGMHLRLGIIPEMPFISEPSLGCTNIRDPSCYTGVNVEIVSMMSQD
LNFTYNFITPEDLKFGGKEWNGLIRDLLDNKTDMIVVALSNNAVRKADID
FSLSMMDGGLGALVKSDGTDLSHPLELLNQDKYQWGVVDSRNPELLLASN
QNADYNRIAEDAVKVGSYGEGLERMRAGGFVFIDEIPGINYATKGECDIV
QIGETFQPFELAFGLRKNSPFKNLVDTFMLGIREQGVISELYAKYENQK
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain4zdm Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4zdm Glycine activated ion channel subunits encoded by ctenophore glutamate receptor genes.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		F66 L95 S96 R101 R147 N148 E191
Binding residue
(residue number reindexed from 1)		F65 L89 S90 R95 R141 N142 E185
Annotation score4
Binding affinityMOAD: Kd=31nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4zdm, PDBe:4zdm, PDBj:4zdm
PDBsum4zdm
PubMed26460032
UniProtH6S0J1

[Back to BioLiP]