Structure of PDB 4zcf Chain A Binding Site BS01

Receptor Information
>4zcf Chain A (length=616) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANSKQLAVLKANFPQCFDKNGAFIQEKLLEIIRASEKESYSLNWLGKSYA
RLLANLPPKTLLAEDKTHNQQEENKNSQHLLIKGDNLEVLKHMVNAYAEK
VKMIYIDPPYNTGKDGFVYNDDRFTPEQLSELAGIDLDEAKRILEFTTKG
SSSHSAWLTFIYPRLYIARELMREDGTIFISIDHNEFSQLKLVCDEIFGE
QNHVGDLVWKNATDNNPSNIAVEHEYIIVYTKNKEQLISEWKSNISDVKN
LLVNIGEEFASKYTGNELQEKYTQWFREHRSELWPLDRYKYIDKDGIYTG
SQSVHNPGKEGYRYDIIHPKTKKPCKQPLMGYRFPLDTMDRLLSEEKIIF
GDDENKIIELKVYAKDYKQKLSSVIHLDGRVATNELKELFPMTQPFNAKT
IKLVEDLISFACDGEGIVLDFFAGSGTTAHTVFNLNNKNKTSYQFITVQL
DEPTKKSDAMKHGYNTIFDLTKERLIRASKKNRDQGFKVYQLMPDFRAKD
ESELTFFDDVVLTPEQYDTLLTTWCLYDGSLLTTPIEDVDLGGYKAHLCD
GRLYLIAPNFTSEALKALLQKVDSDKDFAPNKVVFYGSNFSAKQMELNEA
LKSYANSIELDLVVRN
Ligand information
Receptor-Ligand Complex Structure
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PDB4zcf Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R305 Q319 H322 P324 L346 K373 I374
Binding residue
(residue number reindexed from 1)		R288 Q302 H305 P307 L329 K356 I357
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4zcf, PDBe:4zcf, PDBj:4zcf
PDBsum4zcf
PubMed26067164
UniProtP12364|T3MO_ECOLX Type III restriction-modification enzyme EcoP15I Mod subunit (Gene Name=mod)

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