Structure of PDB 4zag Chain A Binding Site BS01

Receptor Information
>4zag Chain A (length=207) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSGPERITLAMTGASGAQYGLRLLDCLVQEEREVHFLISKAAQLVMATQT
DVALPAKPQAMQAFLTEYCGAAAGQIRVFGQNDWMAPPASGSSAPNAMVI
CPCSTGTLSAVATGACNNLIERAADVALKERRPLVLVPREAPFSSIHLEN
MLKLSNLGAVILPAAPGFYHQPQSVEDLVDFVVARILNTLGIPQDMLPRW
GEQHLVS
Ligand information
Ligand ID4LR
InChIInChI=1S/C5H11O4P/c1-5(2)3-4-9-10(6,7)8/h3H,4H2,1-2H3,(H2,6,7,8)
InChIKeyMQCJHQBRIPSIKA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.9.2CC(=CCOP(=O)(O)O)C
CACTVS 3.385CC(C)=CCO[P](O)(O)=O
ACDLabs 12.01OP(OC\C=C(\C)C)(O)=O
FormulaC5 H11 O4 P
NameDimethylallyl monophosphate
ChEMBLCHEMBL144874
DrugBank
ZINCZINC000002526571
PDB chain4zag Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zag UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis.
Resolution1.68 Å
Binding residue
(original residue number in PDB)		Y169 R185 W200
Binding residue
(residue number reindexed from 1)		Y169 R185 W200
Annotation score5
Binding affinityMOAD: Kd=12uM
Enzymatic activity
Enzyme Commision number 2.5.1.129: flavin prenyltransferase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004659 prenyltransferase activity
GO:0016831 carboxy-lyase activity
GO:0106141 flavin prenyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4zag, PDBe:4zag, PDBj:4zag
PDBsum4zag
PubMed26083743
UniProtQ9HX08|UBIX_PSEAE Flavin prenyltransferase UbiX (Gene Name=ubiX)

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