Structure of PDB 4z9v Chain A Binding Site BS01
Receptor Information
>4z9v Chain A (length=153) Species:
9606
(Homo sapiens) [
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HMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAF
SDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESV
DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRK
GQE
Ligand information
>4z9v Chain C (length=15) Species:
9606
(Homo sapiens) [
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SDIYKIREIADGLCL
Receptor-Ligand Complex Structure
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PDB
4z9v
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.
Resolution
2.099 Å
Binding residue
(original residue number in PDB)
F97 R100 Y101 F105 E129 L130 D133 N136 G138 R139 A142 Y195
Binding residue
(residue number reindexed from 1)
F42 R45 Y46 F50 E74 L75 D78 N81 G83 R84 A87 Y140
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0042981
regulation of apoptotic process
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Biological Process
External links
PDB
RCSB:4z9v
,
PDBe:4z9v
,
PDBj:4z9v
PDBsum
4z9v
PubMed
26813996
UniProt
Q07817
|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)
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