Structure of PDB 4z77 Chain A Binding Site BS01
Receptor Information
>4z77 Chain A (length=277) Species:
10090
(Mus musculus) [
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MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRA
PWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMF
GCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQ
AGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDV
TLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVV
PLGKEQNYTCHVHHKGLPEPLTLRWKP
Ligand information
>4z77 Chain C (length=9) Species:
9606
(Homo sapiens) [
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LYLVCGERV
Receptor-Ligand Complex Structure
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PDB
4z77
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
Resolution
1.85 Å
Binding residue
(original residue number in PDB)
Y7 Q63 R66 D70 W73 V76 S77 Y84 R97 F99 T143 K146 W147 D152 Y155 Y156 Y159 E163 W167
Binding residue
(residue number reindexed from 1)
Y8 Q64 R67 D71 W74 V77 S78 Y85 R98 F100 T144 K147 W148 D153 Y156 Y157 Y160 E164 W168
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4z77
,
PDBe:4z77
,
PDBj:4z77
PDBsum
4z77
PubMed
UniProt
P01902
|HA1D_MOUSE H-2 class I histocompatibility antigen, K-D alpha chain (Gene Name=H2-K1)
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