Structure of PDB 4z0p Chain A Binding Site BS01

Receptor Information
>4z0p Chain A (length=316) Species: 266834 (Sinorhizobium meliloti 1021) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSPVIVDLKFIPEEVEAALAGAFPGREVIDLADPAHQERDLSGIDYAVVW
KSAPDLFSRAPDLKVVFSGGAGVDHVLTLPGLPDVPLVRFVDRTLTTRMS
EWVMMQCLLHLRQHRAYEALAKKHEWRDLSQPEAADVTVGIMGMGVLGQD
AARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTDFLVGLLPLT
PDTRGIFNAALFAKLSRNGPFGAPVFINAGRGGSQVEADILECLDSGVLG
GASLDVFEREPLSPESRFWDMPNVYVTPHVAASSDVRALFVHVEHQIARF
ESGLPLEHVVDKVAGY
Ligand information
Ligand IDOXD
InChIInChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)
InChIKeyMUBZPKHOEPUJKR-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC(=O)C(O)=O
ACDLabs 10.04O=C(O)C(=O)O
OpenEye OEToolkits 1.5.0C(=O)(C(=O)O)O
FormulaC2 H2 O4
NameOXALIC ACID
ChEMBLCHEMBL146755
DrugBankDB03902
ZINCZINC000006021239
PDB chain4z0p Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4z0p Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		W53 G73 A74 G75 R234 H282
Binding residue
(residue number reindexed from 1)		W50 G70 A71 G72 R231 H279
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) L98 R234 G253 D258 E263 H282
Catalytic site (residue number reindexed from 1) L95 R231 G250 D255 E260 H279
Enzyme Commision number 1.1.1.79: glyoxylate reductase (NADP(+)).
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:4z0p, PDBe:4z0p, PDBj:4z0p
PDBsum4z0p
PubMed29309127
UniProtQ92T34

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