Structure of PDB 4z0e Chain A Binding Site BS01

Receptor Information
>4z0e Chain A (length=270) Species: 1036723 (Plasmodium falciparum Vietnam Oak-Knoll (FVO)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIII
ETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLC
SRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDK
LFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSAN
DLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTC
LINNSSYIATTALSHPIEVE
Ligand information
>4z0e Chain C (length=13) Species: 5833 (Plasmodium falciparum) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CWTTRMSPPQQIC
Receptor-Ligand Complex Structure
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PDB4z0e Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
F183 T186 G222 N223 M224 N225 P226 N228 S232 Y234 Y236
Binding residue
(residue number reindexed from 1)
F66 T69 G105 N106 M107 N108 P109 N111 S114 Y116 Y118
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4z0e, PDBe:4z0e, PDBj:4z0e
PDBsum4z0e
PubMed27422009
UniProtA0A024UZE1

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