Structure of PDB 4yoy Chain A Binding Site BS01

Receptor Information
>4yoy Chain A (length=226) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIVAADTGGAVLDESFQPVGLIATVAVLVEKPYKTSKRFLVKYADPYNY
DLSGRQAIRDEIELAIELAREVSPDVIHLNSTLGGIEVRKLDESTIDALQ
ISDRGKEIWKELSKDLQPLAKKFWEETGIEIIAIGKSSVPVRIAEIYAGI
FSVKWALDNVGGLLVGLPRYMEVEIKKDKIIGKSLDPREGGLYGEVKTEV
PQGIKWELYPNPLVRRFMVFEITSKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4yoy Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I
Resolution1.95 Å
Binding residue
(original residue number in PDB)
D7 G9 R55 N80 T82 S102 G105 G169 L170 P171 V217 F220
Binding residue
(residue number reindexed from 1)
D7 G9 R55 N80 T82 S102 G105 G166 L167 P168 V214 F217
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4yoy, PDBe:4yoy, PDBj:4yoy
PDBsum4yoy
PubMed26138487
UniProtA0A060P168

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