Structure of PDB 4yow Chain A Binding Site BS01

Receptor Information
>4yow Chain A (length=227) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIVAADTGGAVLDESFQPVGLIATVAVLVEKPYKTSKRFLVKYADPYNY
DLSGRQAIRDEIELAIELAREVSPDVIHLNSTLGGIEVRKLDESTIDALQ
ISDRGKEIWKELSKDLQPLAKKFWEETGIEIIAIGKSSVPVRIAEIYAGI
FSVKWALDNVKEKGGLLVGLPRYMEVEIKKDKIIGKSLDPREGGLYGEVK
TEVPQGIKWELYPNPLVRRFMVFEITS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4yow Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I
Resolution2.5 Å
Binding residue
(original residue number in PDB)
D7 T8 G9 L22 R55 N80 T82 I101 S102 I108 G169 L170 P171 F220
Binding residue
(residue number reindexed from 1)
D7 T8 G9 L22 R55 N80 T82 I101 S102 I108 G169 L170 P171 F220
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4yow, PDBe:4yow, PDBj:4yow
PDBsum4yow
PubMed26138487
UniProtA0A060P168

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