Structure of PDB 4yot Chain A Binding Site BS01

Receptor Information
>4yot Chain A (length=225) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIVAADTGGAVLDESFQPVGLIATVAVLVEKPYKTSKRFLVKYADPYNY
RQAIRDEIELAIELAREVSPDVIHLDSTLGGIEVRKLDESTIDALQISDR
GKEIWKELSKDLQPLAKKFWEETGIEIIAIGKSSVPVRIAEIYAGIFSVK
WALDNVKEKGGLLVGLPRYMEVEIKKDKIIGKSLDPREGGLYGEVKTEVP
QGIKWELYPNPLVRRFMVFEITSKS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4yot Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4yot Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D7 D80
Binding residue
(residue number reindexed from 1)		D7 D76
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4yot, PDBe:4yot, PDBj:4yot
PDBsum4yot
PubMed26138487
UniProtA0A060P168

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