Structure of PDB 4yos Chain A Binding Site BS01

Receptor Information
>4yos Chain A (length=340) Species: 9606,225400 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETF
CQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDM
SVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIE
VVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTC
EEVIFRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTL
VHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHV
YRSVLLKSEERGDLIKFYNTIYVGRVKSFALKYDPLSPFP
Ligand information
Receptor-Ligand Complex Structure
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PDB4yos Structural mechanisms of DREAM complex assembly and regulation.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
Y849 K853 F861 R869 S876 Y879 R880 N935
Binding residue
(residue number reindexed from 1)
Y271 K275 F283 R291 S298 Y301 R302 N319
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:4yos, PDBe:4yos, PDBj:4yos
PDBsum4yos
PubMed25917549
UniProtL5LUA8;
P28749|RBL1_HUMAN Retinoblastoma-like protein 1 (Gene Name=RBL1)

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