Structure of PDB 4yoo Chain A Binding Site BS01

Receptor Information
>4yoo Chain A (length=343) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETF
CQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDM
SVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIE
VVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTC
EEVIFRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTL
VHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHV
YRSVLLKEERGDLIKFYNTIYVGRVKSFALKYDLAPPLSPFPH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4yoo Structural mechanisms of DREAM complex assembly and regulation.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y849 K853 V854 F861 E863 R869 Y879 R880 I931 Y934 N935
Binding residue
(residue number reindexed from 1)		Y271 K275 V276 F283 E285 R291 Y301 R302 I314 Y317 N318
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:4yoo, PDBe:4yoo, PDBj:4yoo
PDBsum4yoo
PubMed25917549
UniProtP28749|RBL1_HUMAN Retinoblastoma-like protein 1 (Gene Name=RBL1)

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