Structure of PDB 4yjg Chain A Binding Site BS01

Receptor Information
>4yjg Chain A (length=341) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAG
LWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFRE
AVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTE
RLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRG
QIIKVDAPWLKNFIITHDLERGIYNSPLIIPGLQAVTLGGTFQVGNWNEI
NNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFGPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLT
Ligand information
Ligand ID4DD
InChIInChI=1S/C10H15N/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9H,7-8,11H2,1H3/t9-/m1/s1
InChIKeyWECUIGDEWBNQJJ-SECBINFHSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.9.2CC(CCc1ccccc1)N
OpenEye OEToolkits 1.9.2C[C@H](CCc1ccccc1)N
ACDLabs 12.01C(CCc1ccccc1)(N)C
CACTVS 3.385C[CH](N)CCc1ccccc1
CACTVS 3.385C[C@@H](N)CCc1ccccc1
FormulaC10 H15 N
Name(2R)-4-phenylbutan-2-amine
ChEMBL
DrugBank
ZINCZINC000001665103
PDB chain4yjg Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4yjg Crystal structure of DAAO variant
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Y224 F242 G313
Binding residue
(residue number reindexed from 1)		Y224 F242 G313
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) L51 G313 T317
Catalytic site (residue number reindexed from 1) L51 G313 T317
Enzyme Commision number 1.4.3.3: D-amino-acid oxidase.
Gene Ontology
Molecular Function
GO:0003884 D-amino-acid oxidase activity
GO:0016491 oxidoreductase activity
GO:0071949 FAD binding
Biological Process
GO:0006562 proline catabolic process
GO:0007586 digestion
GO:0019478 D-amino acid catabolic process
GO:0036088 D-serine catabolic process
GO:0042416 dopamine biosynthetic process
GO:0046416 D-amino acid metabolic process
GO:0055130 D-alanine catabolic process
GO:0070945 neutrophil-mediated killing of gram-negative bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0042995 cell projection
GO:0045202 synapse
GO:0048786 presynaptic active zone

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4yjg, PDBe:4yjg, PDBj:4yjg
PDBsum4yjg
PubMed
UniProtP00371|OXDA_PIG D-amino-acid oxidase (Gene Name=DAO)

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