Structure of PDB 4yi7 Chain A Binding Site BS01

Receptor Information
>4yi7 Chain A (length=331) Species: 62977 (Acinetobacter baylyi ADP1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RANIQQALNHITKNIHLTQAQMEDVMRSIMQGEATEAQIGALMMGLRMKG
ESIDEITAAARVMRELAIKIDVSDIQYLVDIVGTGGDNLFNVSTASSFVI
AAAGATIAKHGNRSSDLLEQAGINLDLDMQQTERCIREMGVGFLFAMKYA
VGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGA
EHVMVVHSKDGLDEISLASQTYIAELKNGEVTEWVLNPEDVNIPSQTLSG
LIVEDSNASLKLIKDALGRKKSDIGEKAANMIALNAGAGIYVSGLATSYK
QGVALAHDIIYGGQALEKMSILSEFTKALKE
Ligand information
Ligand IDBE2
InChIInChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
InChIKeyRWZYAGGXGHYGMB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Nc1ccccc1C(O)=O
ACDLabs 10.04O=C(O)c1ccccc1N
OpenEye OEToolkits 1.5.0c1ccc(c(c1)C(=O)O)N
FormulaC7 H7 N O2
Name2-AMINOBENZOIC ACID
ChEMBLCHEMBL14173
DrugBankDB04166
ZINCZINC000000047985
PDB chain4yi7 Chain A Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4yi7 Substrate inhibition of protein in tryptophan biosynthesis pathway redirects flux to aromatic catabolism in Acinetobacter baylyi ADP1.
Resolution1.853 Å
Binding residue
(original residue number in PDB)		V81 G82 H111 R168 G181
Binding residue
(residue number reindexed from 1)		V82 G83 H110 R154 G167
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) V81
Catalytic site (residue number reindexed from 1) V82
Enzyme Commision number 2.4.2.18: anthranilate phosphoribosyltransferase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004048 anthranilate phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000162 tryptophan biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4yi7, PDBe:4yi7, PDBj:4yi7
PDBsum4yi7
PubMed
UniProtP00500|TRPD_ACIAD Anthranilate phosphoribosyltransferase (Gene Name=trpD)

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