Structure of PDB 4ygi Chain A Binding Site BS01
Receptor Information
>4ygi Chain A (length=150) Species:
3702
(Arabidopsis thaliana) [
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QIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDDGGELVATSIV
SSGGYNDVLDNSDVLIYTGQGGNVGKKEPPKDQQLVTGNLALKNSINKKN
PVRVIRGIKKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPW
Ligand information
>4ygi Chain B (length=10) [
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actacgtagt
Receptor-Ligand Complex Structure
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PDB
4ygi
Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
Y378 R379 S391 Q392 G394 S413 G415 Y416 D418 Y428 T429 Q431 Y486
Binding residue
(residue number reindexed from 1)
Y17 R18 S30 Q31 G33 S52 G54 Y55 D57 Y67 T68 Q70 Y112
Binding affinity
PDBbind-CN
: Kd=1.5uM
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.367
: [histone H3]-lysine(9) N-methyltransferase.
External links
PDB
RCSB:4ygi
,
PDBe:4ygi
,
PDBj:4ygi
PDBsum
4ygi
PubMed
26841909
UniProt
O82175
|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5 (Gene Name=SUVH5)
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