Structure of PDB 4ygi Chain A Binding Site BS01

Receptor Information
>4ygi Chain A (length=150) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDDGGELVATSIV
SSGGYNDVLDNSDVLIYTGQGGNVGKKEPPKDQQLVTGNLALKNSINKKN
PVRVIRGIKKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ygi Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain
Resolution2.6 Å
Binding residue
(original residue number in PDB)
Y378 R379 S391 Q392 G394 S413 G415 Y416 D418 Y428 T429 Q431 Y486
Binding residue
(residue number reindexed from 1)
Y17 R18 S30 Q31 G33 S52 G54 Y55 D57 Y67 T68 Q70 Y112
Binding affinityPDBbind-CN: Kd=1.5uM
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.367: [histone H3]-lysine(9) N-methyltransferase.
External links
PDB RCSB:4ygi, PDBe:4ygi, PDBj:4ygi
PDBsum4ygi
PubMed26841909
UniProtO82175|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5 (Gene Name=SUVH5)

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