Structure of PDB 4xyi Chain A Binding Site BS01

Receptor Information
>4xyi Chain A (length=375) Species: 402676 (Schizosaccharomyces japonicus yFS275) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEVDLEKKIQEEYKLWKQNVPFLYDLVITEALEWPSLTVEWFPGSERSSI
QKLLLGTQTSGNDQNYLQVASVQLPYGLDIVQKIHHEGDVNKARFMPQNP
DIIATLGLNGNGYIFDLNLYREQPIVQTGHQACLRHHTSEGFGLGWNFIQ
EGTLATGTEDTSICVWDIKGKSLSLEKSIDVAPVSVYHRHTAVVNDLQFH
LQHEALLTSVSDDCTLQIHDTRLPSSSSASQCVKAHEQPVNGVAFNPFND
YLLATASADHTVALWDLRRLNQRLHTLEGHEDEVYNVQWSPHDEPILVTS
STDRRVCVWDLSKIGEEQTVEDSEDGAPELMFMHGGHTNRVSDLSWNPNN
KWVLASLADDNILQIWSPSKVIWAS
Ligand information
>4xyi Chain B (length=13) Species: 402676 (Schizosaccharomyces japonicus yFS275) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ITKPAIRRLARRG
Receptor-Ligand Complex Structure
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PDB4xyi Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		N33 L37 D366 G367 A368 L371 F373 M374
Binding residue
(residue number reindexed from 1)		N19 L23 D325 G326 A327 L330 F332 M333
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042393 histone binding
Biological Process
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0033698 Rpd3L complex
GO:0070210 Rpd3L-Expanded complex
GO:0098654 CENP-A recruiting complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xyi, PDBe:4xyi, PDBj:4xyi
PDBsum4xyi
PubMed26343758
UniProtB6K598

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