Structure of PDB 4xxf Chain A Binding Site BS01

Receptor Information

>4xxf Chain A (length=249) Species: 105987 (Glaciozyma antarctica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GGLAALTKPPTFATVEAERAWLKERLVAAIRIFANEGFDHTVAGHLTVRD
PENKHHFWVNPFGLAFRLMTVSDLILVNQEGTVIGGGKEGRRIVNLAGFM
IHSAIHKARPEVQAICHSHSTYGKAFSSLGKPLAITTQDSCAFYGDVALL
GDESGTIAVALQQKKAIILQNHGLLTVGTTIDSAVAWFIMLEKQCQVQLL
ADAAGQTIPIDEPQAAFTFKELGHEQAGYFQASPYFQVIEHLQGEEYRK

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

4xxf Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4xxf Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.
Resolution	1.34 Å
Binding residue (original residue number in PDB)	H142 H144 H206
Binding residue (residue number reindexed from 1)	H117 H119 H172
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	G123 H142 H144 Q163 H206
Catalytic site (residue number reindexed from 1)	G98 H117 H119 Q138 H172
Enzyme Commision number	4.1.2.17: L-fuculose-phosphate aldolase.

Gene Ontology

	Molecular Function
GO:0008738	L-fuculose-phosphate aldolase activity
GO:0046872	metal ion binding
GO:0051015	actin filament binding

	Cellular Component
GO:0005856	cytoskeleton

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4xxf, PDBe:4xxf, PDBj:4xxf
PDBsum	4xxf
PubMed	27827354
UniProt	A0A0J9X279

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