Structure of PDB 4xoj Chain A Binding Site BS01

Receptor Information
>4xoj Chain A (length=223) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRL
GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV
ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKS
AYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQK
NKPGVYTKVCNYVSWIKQTIASN
Ligand information
Receptor-Ligand Complex Structure
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PDB4xoj Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1).
Resolution0.91 Å
Binding residue
(original residue number in PDB)
F39 H55 S93 N94 T95 Q170 D186 S187 C188 Q189 G190 S192 S207 W208 G209
Binding residue
(residue number reindexed from 1)
F24 H40 S78 N79 T80 Q155 D171 S172 C173 Q174 G175 S177 S192 W193 G194
Enzymatic activity
Catalytic site (original residue number in PDB) H55 D99 Q189 G190 D191 S192 G193
Catalytic site (residue number reindexed from 1) H40 D84 Q174 G175 D176 S177 G178
Enzyme Commision number 3.4.21.4: trypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:4xoj, PDBe:4xoj, PDBj:4xoj
PDBsum4xoj
PubMed26212347
UniProtP00760|TRY1_BOVIN Serine protease 1 (Gene Name=PRSS1)

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