Structure of PDB 4xai Chain A Binding Site BS01

Receptor Information
>4xai Chain A (length=565) Species: 7070,83334 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFPSAICESAAQLIFMNVQWVRSIPAFTCL
PLSDQLLLLEESWLDLFVLGAAQFLPLMDFSVLVEACGVLQQEPHRRDAF
LKEVADFQETLKKISQFQLDAHEFACLRAIVLFKTSFEEKTTTESAKISV
IQDDAQMRLNKHVTTTYPKQPLRFGKILLLVSSTFRTISGRTIEDLFFKK
VIRDTPIVAIISNMY
Ligand information
>4xai Chain P (length=21) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YADTPALRQLSEYARPHVAFS
Receptor-Ligand Complex Structure
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PDB4xai Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E1201 A1204 F1208 K1381 V1382 R1384 V1389 I1392
Binding residue
(residue number reindexed from 1)		E378 A381 F385 K550 V551 R553 V558 I561
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xai, PDBe:4xai, PDBj:4xai
PDBsum4xai
PubMed25691470
UniProtP0AEY0|MALE_ECO57 Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9NCL0

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