Structure of PDB 4x3e Chain A Binding Site BS01
Receptor Information
>4x3e Chain A (length=359) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQG
EIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFG
GVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDY
NPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVC
WKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALG
NQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCD
DASIWRWDR
Ligand information
>4x3e Chain B (length=8) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
AQRKFAQS
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4x3e
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
F97 Y148 Y308 D362 I363 W364 Y365 A411 R414
Binding residue
(residue number reindexed from 1)
F17 Y68 Y228 D282 I283 W284 Y285 A331 R334
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4x3e
,
PDBe:4x3e
,
PDBj:4x3e
PDBsum
4x3e
PubMed
25620564
UniProt
O75530
|EED_HUMAN Polycomb protein EED (Gene Name=EED)
[
Back to BioLiP
]
