Structure of PDB 4x33 Chain A Binding Site BS01

Receptor Information

>4x33 Chain A (length=60) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

STYDEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKVAVCPSCS
LMIDVVHHHH

Ligand information

InChI=1S/Fe/q+3

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Fe

Name

FE (III) ION

PDB chain

4x33 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	4x33 Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification.
Resolution	1.45 Å
Binding residue (original residue number in PDB)	C25 C27 C47 C50
Binding residue (residue number reindexed from 1)	C24 C26 C46 C49
Annotation score	5

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:4x33, PDBe:4x33, PDBj:4x33
PDBsum	4x33
PubMed	25604895
UniProt	Q3E840\|DPH3_YEAST Diphthamide biosynthesis protein 3 (Gene Name=KTI11)

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