Structure of PDB 4wzx Chain A Binding Site BS01
Receptor Information
>4wzx Chain A (length=87) Species:
9606
(Homo sapiens) [
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TSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGE
LLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKM
Ligand information
>4wzx Chain E (length=16) Species:
9606
(Homo sapiens) [
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DIDFDDLSRRFEELKK
Receptor-Ligand Complex Structure
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PDB
4wzx
ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
Resolution
1.3859 Å
Binding residue
(original residue number in PDB)
Q56 G60 L63 L66 A67 R75 H79 M86 A89 E90 K93
Binding residue
(residue number reindexed from 1)
Q45 G49 L52 L55 A56 R64 H68 M75 A78 E79 K82
Enzymatic activity
Enzyme Commision number
2.7.11.1
: non-specific serine/threonine protein kinase.
External links
PDB
RCSB:4wzx
,
PDBe:4wzx
,
PDBj:4wzx
PDBsum
4wzx
PubMed
26011858
UniProt
Q6PHR2
|ULK3_HUMAN Serine/threonine-protein kinase ULK3 (Gene Name=ULK3)
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