Structure of PDB 4wzw Chain A Binding Site BS01

Receptor Information
>4wzw Chain A (length=505) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTNYDIVVRAKQMWEILRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHD
STRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSK
PQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGN
TFQLYKSADHPTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLV
HKVFLDFFTYAPPKLRSEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPK
DRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISS
LPSIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEVR
RRELLESISPALLSYLQEHAQEVVLDKSACVLVSDILGSATGDVQPTMNA
IASLAATGLHPLHIAEHPAGHLVLKWLIEQDKKMKENGREGCFAKTLVEH
VGMKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKGIE
ILLEK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4wzw A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.
Resolution2.9516 Å
Binding residue
(original residue number in PDB)		R268 H362 V455
Binding residue
(residue number reindexed from 1)		R140 H234 V327
Binding affinityPDBbind-CN: Kd=84.1nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4wzw, PDBe:4wzw, PDBj:4wzw
PDBsum4wzw
PubMed25512524
UniProtQ15397|PUM3_HUMAN Pumilio homolog 3 (Gene Name=PUM3)

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