Structure of PDB 4wwb Chain A Binding Site BS01

Receptor Information
>4wwb Chain A (length=112) Species: 266264 (Cupriavidus metallidurans CH34) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHGDLHEILHEAVPLDANEREILELKEDAFAQRRREIETRLRAANGKLAD
AIAKNPAWSPEVEAATQEVERAAGDLQRATLVHVFEMRAGLKPEHRPAFD
RVLIDALRRGSQ
Ligand information
Ligand IDNI
InChIInChI=1S/Ni/q+2
InChIKeyVEQPNABPJHWNSG-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ni++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ni+2]
FormulaNi
NameNICKEL (II) ION
ChEMBL
DrugBankDB14204
ZINC
PDB chain4wwb Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4wwb Response of CnrX from Cupriavidus metallidurans CH34 to nickel binding.
Resolution1.11 Å
Binding residue
(original residue number in PDB)		H42 H46 E63 H119 M123
Binding residue
(residue number reindexed from 1)		H6 H10 E27 H83 M87
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0042597 periplasmic space

View graph for
Cellular Component
External links
PDB RCSB:4wwb, PDBe:4wwb, PDBj:4wwb
PDBsum4wwb
PubMed25628016
UniProtP37975|CNRR_CUPMC Nickel and cobalt resistance protein CnrR (Gene Name=cnrR)

[Back to BioLiP]